3cbk: Difference between revisions
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{{STRUCTURE_3cbk| PDB=3cbk | SCENE= }} | {{STRUCTURE_3cbk| PDB=3cbk | SCENE= }} | ||
===chagasin-cathepsin B=== | ===chagasin-cathepsin B=== | ||
{{ABSTRACT_PUBMED_18515357}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | |||
==About this Structure== | ==About this Structure== | ||
[[3cbk]] is a 2 chain structure | [[3cbk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBK OCA]. | ||
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018515357</ref><references group="xtra"/> | <ref group="xtra">PMID:018515357</ref><references group="xtra"/><references/> | ||
[[Category: Cathepsin B]] | [[Category: Cathepsin B]] | ||
[[Category: Abrahamson, M.]] | [[Category: Abrahamson, M.]] | ||
[[Category: Bujacz, G D.]] | [[Category: Bujacz, G D.]] | ||
Revision as of 12:14, 19 March 2014
chagasin-cathepsin Bchagasin-cathepsin B
Template:ABSTRACT PUBMED 18515357
FunctionFunction
[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
About this StructureAbout this Structure
3cbk is a 2 chain structure. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Redzynia I, Ljunggren A, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G. Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J Biol Chem. 2008 Aug 15;283(33):22815-25. Epub 2008 May 30. PMID:18515357 doi:10.1074/jbc.M802064200