1w6h: Difference between revisions

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[[Image:1w6h.png|left|200px]]
==NOVEL PLASMEPSIN II-INHIBITOR COMPLEX==
 
<StructureSection load='1w6h' size='340' side='right' caption='[[1w6h]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
{{STRUCTURE_1w6h|  PDB=1w6h  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W6H FirstGlance]. <br>
===NOVEL PLASMEPSIN II-INHIBITOR COMPLEX===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TIT:N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE'>TIT</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j8j|1j8j]], [[1lee|1lee]], [[1lf2|1lf2]], [[1lf3|1lf3]], [[1lf4|1lf4]], [[1m43|1m43]], [[1me6|1me6]], [[1pfz|1pfz]], [[1sme|1sme]], [[1w6i|1w6i]], [[1xdh|1xdh]], [[1xe5|1xe5]], [[1xe6|1xe6]], [[2bju|2bju]], [[2bl3|2bl3]]</td></tr>
 
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Plasmepsin_II Plasmepsin II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.39 3.4.23.39] </span></td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w6h RCSB], [http://www.ebi.ac.uk/pdbsum/1w6h PDBsum]</span></td></tr>
[[1w6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6H OCA].  
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/1w6h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Plasmepsin|Plasmepsin]]
*[[Plasmepsin|Plasmepsin]]
__TOC__
</StructureSection>
[[Category: Plasmepsin II]]
[[Category: Plasmepsin II]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]

Revision as of 00:03, 29 September 2014

NOVEL PLASMEPSIN II-INHIBITOR COMPLEXNOVEL PLASMEPSIN II-INHIBITOR COMPLEX

Structural highlights

1w6h is a 2 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Related:1j8j, 1lee, 1lf2, 1lf3, 1lf4, 1m43, 1me6, 1pfz, 1sme, 1w6i, 1xdh, 1xe5, 1xe6, 2bju, 2bl3
Activity:Plasmepsin II, with EC number 3.4.23.39
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1w6h, resolution 2.24Å

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