3fl4: Difference between revisions

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[[Image:3fl4.png|left|200px]]
==P38 kinase crystal structure in complex with RO5634==
 
<StructureSection load='3fl4' size='340' side='right' caption='[[3fl4]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
{{STRUCTURE_3fl4|  PDB=3fl4  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3fl4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FL4 FirstGlance]. <br>
===P38 kinase crystal structure in complex with RO5634===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FL4:6-(2,4-DIFLUOROPHENOXY)-3-(2-METHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE'>FL4</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fi4|3fi4]], [[3fkl|3fkl]], [[3fkn|3fkn]], [[3fko|3fko]]</td></tr>
 
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr>
[[3fl4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL4 OCA].  
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fl4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fl4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fl4 RCSB], [http://www.ebi.ac.uk/pdbsum/3fl4 PDBsum]</span></td></tr>
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/3fl4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]

Revision as of 16:39, 29 September 2014

P38 kinase crystal structure in complex with RO5634P38 kinase crystal structure in complex with RO5634

Structural highlights

3fl4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Related:3fi4, 3fkl, 3fkn, 3fko
Gene:CSBP, CSBP1, CSBP2, CSPB1, MAPK14, MXI2 (Homo sapiens)
Activity:Mitogen-activated protein kinase, with EC number 2.7.11.24
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3fl4, resolution 1.80Å

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OCA