1kph: Difference between revisions

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[[Image:1kph.gif|left|200px]]<br /><applet load="1kph" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kph.gif|left|200px]]
caption="1kph, resolution 2.00&Aring;" />
 
'''Crystal Structure of mycolic acid cyclopropane synthase CmaA1 complexed with SAH and DDDMAB'''<br />
{{Structure
|PDB= 1kph |SIZE=350|CAPTION= <scene name='initialview01'>1kph</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=10A:DIDECYL-DIMETHYL-AMMONIUM'>10A</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cyclopropane-fatty-acyl-phospholipid_synthase Cyclopropane-fatty-acyl-phospholipid synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.79 2.1.1.79]
|GENE= cmaA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal Structure of mycolic acid cyclopropane synthase CmaA1 complexed with SAH and DDDMAB'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KPH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=CO3:'>CO3</scene>, <scene name='pdbligand=SAH:'>SAH</scene> and <scene name='pdbligand=10A:'>10A</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cyclopropane-fatty-acyl-phospholipid_synthase Cyclopropane-fatty-acyl-phospholipid synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.79 2.1.1.79] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPH OCA].  
1KPH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KPH OCA].  


==Reference==
==Reference==
Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis., Huang CC, Smith CV, Glickman MS, Jacobs WR Jr, Sacchettini JC, J Biol Chem. 2002 Mar 29;277(13):11559-69. Epub 2001 Dec 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11756461 11756461]
Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis., Huang CC, Smith CV, Glickman MS, Jacobs WR Jr, Sacchettini JC, J Biol Chem. 2002 Mar 29;277(13):11559-69. Epub 2001 Dec 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11756461 11756461]
[[Category: Cyclopropane-fatty-acyl-phospholipid synthase]]
[[Category: Cyclopropane-fatty-acyl-phospholipid synthase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]


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