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<big><b>Proposed title: Knots in Proteins: Methods</b></big>
<big><b>Proposed title: Knots in Proteins: Methods</b></big>


This page describes technical details of the methods used for the morph at [[Knots in Proteins]].
This page describes technical details of the methods used for the morph at [[Knots in proteins]].


The [[PDB file]] that displays the animated morph of the protein knot being "shrunk" is [[Image:1yve i knot morph.pdb]]. This file contains 51 models. Model 1 is a slightly smoothed backbone trace of the knotted segment of chain I in [[1yve]], namely 234 residues, sequence numbers 312-545. Model 51 is a simplified knot, which is the result of shrinking the backbone while keeping the ends fixed in space. These models were kindly provided by William R. Taylor ([http://mathbio.nimr.mrc.ac.uk/ Division of Mathematical Biology, National Institute for Medical Research, the Ridgeway, Mill Hill, London UK]). These models represent the residues with alpha carbon atoms only, and all residues are labeled GLY.
The [[PDB file]] that displays the animated morph of the protein knot being "shrunk" is [[Image:1yve i knot morph.pdb]]. This file contains 51 models. Model 1 is a slightly smoothed backbone trace of the knotted segment of chain I in [[1yve]], namely 234 residues, sequence numbers 312-545. Model 51 is a simplified knot, which is the result of shrinking the backbone while keeping the ends fixed in space. These models were kindly provided by William R. Taylor ([http://mathbio.nimr.mrc.ac.uk/ Division of Mathematical Biology, National Institute for Medical Research, the Ridgeway, Mill Hill, London UK]). These models represent the residues with alpha carbon atoms only, and all residues are labeled GLY.