1k8t: Difference between revisions

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[[Image:1k8t.gif|left|200px]]<br /><applet load="1k8t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1k8t.gif|left|200px]]
caption="1k8t, resolution 2.6&Aring;" />
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF)'''<br />
{{Structure
|PDB= 1k8t |SIZE=350|CAPTION= <scene name='initialview01'>1k8t</scene>, resolution 2.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NI:NICKEL (II) ION'>NI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1]
|GENE=
}}
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1K8T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=NI:'>NI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1K8T with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb28_1.html Anthrax Toxin]]. Active as [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8T OCA].  
1K8T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. The following page contains interesting information on the relation of 1K8T with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb28_1.html Anthrax Toxin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8T OCA].  


==Reference==
==Reference==
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin., Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ, Nature. 2002 Jan 24;415(6870):396-402. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11807546 11807546]
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin., Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ, Nature. 2002 Jan 24;415(6870):396-402. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11807546 11807546]
[[Category: Adenylate cyclase]]
[[Category: Adenylate cyclase]]
[[Category: Anthrax Toxin]]
[[Category: Anthrax Toxin]]
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[[Category: edema factor]]
[[Category: edema factor]]


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