1jlf: Difference between revisions

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-[[Image:1jlf.gif|left|200px]]<br /><applet load="1jlf" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1jlf.gif|left|200px]]
-caption="1jlf, resolution 2.60&Aring;" />
-'''CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE'''<br />
+ {{Structure
+|PDB= 1jlf |SIZE=350|CAPTION= <scene name='initialview01'>1jlf</scene>, resolution 2.60&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NVP:11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE'>NVP</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
+|GENE= POl ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Human immunodeficiency virus type 1 (isolate HXB2)]), POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= Human immunodeficiency virus type 1 (isolate HXB2)])
+}}
+'''CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-JLF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)] with <scene name='pdbligand=NVP:'>NVP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLF OCA].
+JLF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_hxb2) Human immunodeficiency virus type 1 (isolate hxb2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLF OCA].
 ==Reference==
-Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors., Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK, J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11575933 11575933]
+Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors., Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK, J Mol Biol. 2001 Sep 28;312(4):795-805. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11575933 11575933]
 [[Category: Human immunodeficiency virus type 1 (isolate hxb2)]]
 [[Category: Protein complex]]
@@ Line 23: / Line 32: @@
 [[Category: Weaver, K.]]
 [[Category: NVP]]
-[[Category: aids]]
+[[Category: aid]]
 [[Category: drug design]]
-[[Category: drug resistance mutations]]
+[[Category: drug resistance mutation]]
 [[Category: hiv-1 reverse transcriptase]]
 [[Category: nevirapine]]
 [[Category: non-nucleoside inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:23:59 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:05:01 2008''