StudioG24SecL04Tpc5: Difference between revisions

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===Invariable===
===Invariable===
Invariable Region:<scene name='StudioG24SecL04Tpc5/Invariable_regions/1'>IR</scene>
Invariable Region:<scene name='StudioG24SecL04Tpc5/Invariable_regions/1'>IR</scene>
The small invariable regions within the variable region as well as the larger invariable domains C & N terminals are not antigenic in natural infections and tend to be conserved among different isolates of the organism.  Conserved portions are probably responsible for the maintenance of the functional and molecular conformations of the VlsE.
The small invariable regions within the variable region as well as the larger invariable domains C & N terminals are not antigenic in natural infections and tend to be conserved among different isolates of the organism.  Conserved portions are probably responsible for the maintenance of the functional and molecular conformations of the VlsE. They maintain the secondary structure of the protein, the beta sheets and alpha helix. This allows the protein to maintain its functional properties because the alpha and beta sheets allow the secondary structure to be stable enough to allow the side chains of the VlsE protein to construct a biologically active tertiary structure.  


====Invariable Region 6 (IR6)====


==Antigenicity==
==Antigenicity==

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Tasfik Ahmed, Justin Thomas, Naveen Pillai, Saad Khamisa