G18secL03Tpc4: Difference between revisions
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=== Role of OspC in Lyme Disease === | === Role of OspC in Lyme Disease === | ||
=== OspC-based Vaccine Against Lyme Disease === | === OspC-based Vaccine Against Lyme Disease === | ||
Researchers believe that an OspC based vaccine would be more effective against Lyme disease than the current OspA based vaccine once further research is conducted regarding the three dimensional structure of OspC's, especially the structure of invasive strains. | Researchers believe that an OspC based vaccine would be more effective against Lyme disease than the current OspA based vaccine once further research is conducted regarding the three dimensional structure of OspC's, especially the structure of invasive strains <ref>D. Kumaran1, S. Eswaramoorthy1, B.J. Luft2, S. Koide3, J.J. Dunn1, C.L. Lawson1,4 and S. Swaminathan1. Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi.The EMBO Journal (2001) 20, 971 - 978 [http://dx.doi.org/DOI:10.1093/emboj/20.5.971]</ref>. | ||
==== Main Advantages of Developing OspC-based Vaccine ==== | ==== Main Advantages of Developing OspC-based Vaccine ==== | ||
==== Main Problems with Application of OspC-based Vaccine ==== | ==== Main Problems with Application of OspC-based Vaccine ==== | ||
'''Notes and References'''<references/> | '''Notes and References'''<references/> | ||