1iqv: Difference between revisions
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[[Image:1iqv.gif|left|200px]] | [[Image:1iqv.gif|left|200px]] | ||
'''Crystal Structure Analysis of the archaebacterial ribosomal protein S7''' | {{Structure | ||
|PDB= 1iqv |SIZE=350|CAPTION= <scene name='initialview01'>1iqv</scene>, resolution 2.1Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= | |||
|GENE= PH1541 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii]) | |||
}} | |||
'''Crystal Structure Analysis of the archaebacterial ribosomal protein S7''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1IQV is a [ | 1IQV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IQV OCA]. | ||
==Reference== | ==Reference== | ||
The structure of the archaebacterial ribosomal protein S7 and its possible interaction with 16S rRNA., Hosaka H, Yao M, Kimura M, Tanaka I, J Biochem. 2001 Nov;130(5):695-701. PMID:[http:// | The structure of the archaebacterial ribosomal protein S7 and its possible interaction with 16S rRNA., Hosaka H, Yao M, Kimura M, Tanaka I, J Biochem. 2001 Nov;130(5):695-701. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11686933 11686933] | ||
[[Category: Pyrococcus horikoshii]] | [[Category: Pyrococcus horikoshii]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: rna-binding]] | [[Category: rna-binding]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:53:41 2008'' | ||
Revision as of 12:53, 20 March 2008
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| , resolution 2.1Å | |||||||
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| Gene: | PH1541 (Pyrococcus horikoshii) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure Analysis of the archaebacterial ribosomal protein S7
OverviewOverview
Ribosomal protein S7 is one of the ubiquitous components of the small subunit of the ribosome. It is a 16S rRNA-binding protein positioned close to the exit of the tRNA, and it plays a role in initiating assembly of the head of the 30S subunit. Previous structural analyses of eubacterial S7 have shown that it has a stable alpha-helix core and a flexible beta-arm. Unlike these eubacterial proteins, archaebacterial or eukaryotic S7 has an N-terminal extension of approximately 60 residues. The crystal structure of S7 from archaebacterium Pyrococcus horikoshii (PhoS7) has been determined at 2.1 A resolution. The final model of PhoS7 consists of six major alpha-helices, a short 3(10)-helix and two beta-stands. The major part (residues 18-45) of the N-terminal extension of PhoS7 reinforces the alpha-helical core by well-extended hydrophobic interactions, while the other part (residues 46-63) is not visible in the crystal and is possibly fixed only by interacting with 16S rRNA. These differences in the N-terminal extension as well as in the insertion (between alpha1 and alpha2) of the archaebacterial S7 structure from eubacterial S7 are such that they do not necessitate a major change in the structure of the currently available eubacterial 16S rRNA. Some of the inserted chains might pass through gaps formed by helices of the 16S rRNA.
About this StructureAbout this Structure
1IQV is a Single protein structure of sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA.
ReferenceReference
The structure of the archaebacterial ribosomal protein S7 and its possible interaction with 16S rRNA., Hosaka H, Yao M, Kimura M, Tanaka I, J Biochem. 2001 Nov;130(5):695-701. PMID:11686933
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