3o1g: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3o1g]] is a 1 chain structure | [[3o1g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O1G OCA]. | ||
==See Also== | ==See Also== | ||
Revision as of 22:17, 20 October 2012
Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.
Template:ABSTRACT PUBMED 20843687
About this StructureAbout this Structure
3o1g is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Finlay W, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Arbuckle W, Anderson M, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Jones P, Uitdehaag JC, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG. Bioorg Med Chem Lett. 2010 Aug 24. PMID:20843687 doi:10.1016/j.bmcl.2010.08.101