1g3n: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:1g3n.jpg|left|200px]] | [[Image:1g3n.jpg|left|200px]] | ||
'''STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX''' | {{Structure | ||
|PDB= 1g3n |SIZE=350|CAPTION= <scene name='initialview01'>1g3n</scene>, resolution 2.9Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | |||
|GENE= CYCLIN-DEPENDENT KINASE 6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), P18(INK4C) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), K-CYCLIN (VIRAL CYCLIND HOMOLOG) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10376 Human herpesvirus 4]) | |||
}} | |||
'''STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX''' | |||
==Overview== | ==Overview== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
1G3N is a [ | 1G3N is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G3N OCA]. | ||
==Reference== | ==Reference== | ||
Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors., Jeffrey PD, Tong L, Pavletich NP, Genes Dev. 2000 Dec 15;14(24):3115-25. PMID:[http:// | Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors., Jeffrey PD, Tong L, Pavletich NP, Genes Dev. 2000 Dec 15;14(24):3115-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11124804 11124804] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Human herpesvirus 4]] | [[Category: Human herpesvirus 4]] | ||
Line 22: | Line 31: | ||
[[Category: viral cyclin]] | [[Category: viral cyclin]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:17:44 2008'' |