1g1x: Difference between revisions

Revision as of 12:17, 20 March 2008

, resolution 2.6Å

Coordinates:

STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA

OverviewOverview

The crystal structure of a 70-kilodalton ribonucleoprotein complex from the central domain of the Thermus thermophilus 30S ribosomal subunit was solved at 2.6 angstrom resolution. The complex consists of a 104-nucleotide RNA fragment composed of two three-helix junctions that lie at the end of a central helix, and the ribosomal proteins S15, S6, and S18. S15 binds the ribosomal RNA early in the assembly of the 30S ribosomal subunit, stabilizing a conformational reorganization of the two three-helix junctions that creates the RNA fold necessary for subsequent binding of S6 and S18. The structure of the complex demonstrates the central role of S15-induced reorganization of central domain RNA for the subsequent steps of ribosome assembly.

About this StructureAbout this Structure

1G1X is a Protein complex structure of sequences from Thermus thermophilus. This structure supersedes the now removed PDB entry 1EKC. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:10753109

Page seeded by OCA on Thu Mar 20 11:17:01 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:1g1x.gif|left|200px]]<br /><applet load="1g1x" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1g1x.gif|left|200px]]
-caption="1g1x, resolution 2.6&Aring;" />
-'''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''<br />
+ {{Structure
+|PDB= 1g1x |SIZE=350|CAPTION= <scene name='initialview01'>1g1x</scene>, resolution 2.6&Aring;
+|SITE=
+|LIGAND=
+|ACTIVITY=
+|GENE=
+}}
+'''STRUCTURE OF RIBOSOMAL PROTEINS S15, S6, S18, AND 16S RIBOSOMAL RNA'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-G1X is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry 1EKC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
+G1X is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. This structure supersedes the now removed PDB entry 1EKC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G1X OCA].
 ==Reference==
-Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10753109 10753109]
+Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain., Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD, Williamson JR, Science. 2000 Apr 7;288(5463):107-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10753109 10753109]
 [[Category: Protein complex]]
 [[Category: Thermus thermophilus]]
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 [[Category: s6]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:45:08 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:17:01 2008''