1e6a: Difference between revisions

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[[Image:1e6a.gif|left|200px]]<br /><applet load="1e6a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1e6a.gif|left|200px]]
caption="1e6a, resolution 1.90&Aring;" />
 
'''FLUORIDE-INHIBITED SUBSTRATE COMPLEX OF SACCHAROMYCES CEREVISIAE INORGANIC PYROPHOSPHATASE'''<br />
{{Structure
|PDB= 1e6a |SIZE=350|CAPTION= <scene name='initialview01'>1e6a</scene>, resolution 1.90&Aring;
|SITE= <scene name='pdbsite=POA:Pop+Binding+Site+For+Chain+A'>POA</scene> and <scene name='pdbsite=POB:Pop+Binding+Site+For+Chain+A'>POB</scene>
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene> and <scene name='pdbligand=POP:PYROPHOSPHATE 2-'>POP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1]
|GENE= PPA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''FLUORIDE-INHIBITED SUBSTRATE COMPLEX OF SACCHAROMYCES CEREVISIAE INORGANIC PYROPHOSPHATASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1E6A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=F:'>F</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=POP:'>POP</scene> and <scene name='pdbligand=POP:'>POP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] Known structural/functional Sites: <scene name='pdbsite=POA:Pop+Binding+Site+For+Chain+A'>POA</scene> and <scene name='pdbsite=POB:Pop+Binding+Site+For+Chain+A'>POB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E6A OCA].  
1E6A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E6A OCA].  


==Reference==
==Reference==
Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase., Heikinheimo P, Tuominen V, Ahonen AK, Teplyakov A, Cooperman BS, Baykov AA, Lahti R, Goldman A, Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3121-6. Epub 2001 Mar 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11248042 11248042]
Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase., Heikinheimo P, Tuominen V, Ahonen AK, Teplyakov A, Cooperman BS, Baykov AA, Lahti R, Goldman A, Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3121-6. Epub 2001 Mar 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11248042 11248042]
[[Category: Inorganic diphosphatase]]
[[Category: Inorganic diphosphatase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: phosphoryl transfer]]
[[Category: phosphoryl transfer]]


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