3gnv: Difference between revisions
Jump to navigation
Jump to search
m Protected "3gnv" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[3gnv]] is a 2 chain structure | [[3gnv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_isolate_hc-j4 Hepatitis c virus isolate hc-j4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GNV OCA]. | ||
==See Also== | ==See Also== | ||
| Line 15: | Line 15: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019507864</ref><references group="xtra"/> | <ref group="xtra">PMID:019507864</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus isolate]] | [[Category: Hepatitis c virus isolate hc-j4]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Bondt, H De.]] | [[Category: Bondt, H De.]] | ||
Revision as of 13:26, 20 October 2012
HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1bHCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 1b
Template:ABSTRACT PUBMED 19507864
About this StructureAbout this Structure
3gnv is a 2 chain structure with sequence from Hepatitis c virus isolate hc-j4. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Vandyck K, Cummings MD, Nyanguile O, Boutton CW, Vendeville S, McGowan D, Devogelaere B, Amssoms K, Last S, Rombauts K, Tahri A, Lory P, Hu L, Beauchamp DA, Simmen K, Raboisson P. Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase. J Med Chem. 2009 Jul 23;52(14):4099-102. PMID:19507864 doi:10.1021/jm9005548
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Hepatitis c virus isolate hc-j4
- RNA-directed RNA polymerase
- Bondt, H De.
- Nyanguile, O.
- 1 5-benzodiazepine
- Apoptosis
- Atp-binding
- Capsid protein
- Cell membrane
- Endoplasmic reticulum
- Envelope protein
- Fusion protein
- Glycoprotein
- Helicase
- Hepatitis c virus
- Host-virus interaction
- Hydrolase
- Interferon antiviral system evasion
- Lipid droplet
- Lipoprotein
- Membrane
- Metal-binding
- Mitochondrion
- Multifunctional enzyme
- Ns5b
- Nucleotide-binding
- Nucleotidyltransferase
- Nucleus
- Oncogene
- Palmitate
- Phosphoprotein
- Polymerase
- Protease
- Ribonucleoprotein
- Rna replication
- Rna-binding
- Rna-directed rna polymerase
- Secreted
- Serine protease
- Sh3-binding
- Sulfone
- Thiol protease
- Transcription
- Transcription regulation
- Transferase
- Transmembrane
- Viral nucleoprotein
- Virion