1c2k: Difference between revisions

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OCA

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-[[Image:1c2k.gif|left|200px]]<br /><applet load="1c2k" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1c2k.gif|left|200px]]
-caption="1c2k, resolution 1.65&Aring;" />
-'''RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES'''<br />
+ {{Structure
+|PDB= 1c2k |SIZE=350|CAPTION= <scene name='initialview01'>1c2k</scene>, resolution 1.65&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=ABI:5-AMIDINO-BENZIMIDAZOLE'>ABI</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4]
+|GENE=
+}}
+'''RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-C2K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=ABI:'>ABI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2K OCA].
+C2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C2K OCA].
 ==Reference==
-Design of potent selective zinc-mediated serine protease inhibitors., Katz BA, Clark JM, Finer-Moore JS, Jenkins TE, Johnson CR, Ross MJ, Luong C, Moore WR, Stroud RM, Nature. 1998 Feb 5;391(6667):608-12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9468142 9468142]
+Design of potent selective zinc-mediated serine protease inhibitors., Katz BA, Clark JM, Finer-Moore JS, Jenkins TE, Johnson CR, Ross MJ, Luong C, Moore WR, Stroud RM, Nature. 1998 Feb 5;391(6667):608-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9468142 9468142]
 [[Category: Bos taurus]]
 [[Category: Single protein]]
@@ Line 23: / Line 32: @@
 [[Category: serine protease/inhibitor]]
 [[Category: zn(ii) affinity stucture-based drug design]]
-[[Category: zn(ii)-mediated serine protease inhibitors]]
+[[Category: zn(ii)-mediated serine protease inhibitor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:01:43 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:19:03 2008''