1bqi: Difference between revisions

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[[Image:1bqi.gif|left|200px]]<br /><applet load="1bqi" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1bqi.gif|left|200px]]
caption="1bqi, resolution 2.5&Aring;" />
 
'''USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES.'''<br />
{{Structure
|PDB= 1bqi |SIZE=350|CAPTION= <scene name='initialview01'>1bqi</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SBA:CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE'>SBA</scene>
|ACTIVITY=
|GENE=
}}
 
'''USE OF PAPAIN AS A MODEL FOR THE STRUCTURE-BASED DESIGN OF CATHEPSIN K INHIBITORS. CRYSTAL STRUCTURES OF TWO PAPAIN INHIBITOR COMPLEXES DEMONSTRATE BINDING TO S'-SUBSITES.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1BQI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya] with <scene name='pdbligand=SBA:'>SBA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BQI OCA].  
1BQI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BQI OCA].  


==Reference==
==Reference==
Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites., LaLonde JM, Zhao B, Smith WW, Janson CA, DesJarlais RL, Tomaszek TA, Carr TJ, Thompson SK, Oh HJ, Yamashita DS, Veber DF, Abdel-Meguid SS, J Med Chem. 1998 Nov 5;41(23):4567-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9804696 9804696]
Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites., LaLonde JM, Zhao B, Smith WW, Janson CA, DesJarlais RL, Tomaszek TA, Carr TJ, Thompson SK, Oh HJ, Yamashita DS, Veber DF, Abdel-Meguid SS, J Med Chem. 1998 Nov 5;41(23):4567-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9804696 9804696]
[[Category: Carica papaya]]
[[Category: Carica papaya]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sulfhydryl proteinase]]
[[Category: sulfhydryl proteinase]]


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