1b6l: Difference between revisions
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[[Image:1b6l.jpg|left|200px]] | [[Image:1b6l.jpg|left|200px]] | ||
'''HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4''' | {{Structure | ||
|PDB= 1b6l |SIZE=350|CAPTION= <scene name='initialview01'>1b6l</scene>, resolution 1.75Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=PI4:1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE'>PI4</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] | |||
|GENE= | |||
}} | |||
'''HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1B6L is a [ | 1B6L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_(isolate_arv2/sf2) Human immunodeficiency virus type 1 (isolate arv2/sf2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6L OCA]. | ||
==Reference== | ==Reference== | ||
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease., Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP, Biochemistry. 1999 Jun 22;38(25):7978-88. PMID:[http:// | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease., Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP, Biochemistry. 1999 Jun 22;38(25):7978-88. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10387041 10387041] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus type 1 (isolate arv2/sf2)]] | [[Category: Human immunodeficiency virus type 1 (isolate arv2/sf2)]] | ||
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[[Category: complex (acid proteinase/peptide)]] | [[Category: complex (acid proteinase/peptide)]] | ||
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