1b2l: Difference between revisions
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[[Image:1b2l.jpg|left|200px]] | [[Image:1b2l.jpg|left|200px]] | ||
'''ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE''' | {{Structure | ||
|PDB= 1b2l |SIZE=350|CAPTION= <scene name='initialview01'>1b2l</scene>, resolution 1.6Å | |||
|SITE= <scene name='pdbsite=ACA:Catalytic+Triad'>ACA</scene>, <scene name='pdbsite=CAA:Ca2++Binding+Residues'>CAA</scene>, <scene name='pdbsite=NA1:Nad+Binding+Motif+In+Dadhs+G(A)Xgxxg'>NA1</scene>, <scene name='pdbsite=NA2:Nad+Binding+Motif+In+Sdrs+Gxxxgxg'>NA2</scene> and <scene name='pdbsite=NA3:Nad/Nadp+Selectivity+Amino+Acid'>NA3</scene> | |||
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NDC:NICOTINAMIDE+ADENINE+DINUCLEOTIDE+CYCLOHEXANONE'>NDC</scene>, <scene name='pdbligand=CYH:CYCLOHEXANONE'>CYH</scene> and <scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] | |||
|GENE= | |||
}} | |||
'''ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS: TERNARY COMPLEX WITH NAD-CYCLOHEXANONE''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1B2L is a [ | 1B2L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Scaptodrosophila_lebanonensis Scaptodrosophila lebanonensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B2L OCA]. | ||
==Reference== | ==Reference== | ||
The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography., Benach J, Atrian S, Gonzalez-Duarte R, Ladenstein R, J Mol Biol. 1999 Jun 4;289(2):335-55. PMID:[http:// | The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography., Benach J, Atrian S, Gonzalez-Duarte R, Ladenstein R, J Mol Biol. 1999 Jun 4;289(2):335-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10366509 10366509] | ||
[[Category: Alcohol dehydrogenase]] | [[Category: Alcohol dehydrogenase]] | ||
[[Category: Scaptodrosophila lebanonensis]] | [[Category: Scaptodrosophila lebanonensis]] | ||
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[[Category: nad- cyclohexanone adduct]] | [[Category: nad- cyclohexanone adduct]] | ||
[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
[[Category: short-chain dehydrogenases/ | [[Category: short-chain dehydrogenases/reductase]] | ||
[[Category: ternary complex]] | [[Category: ternary complex]] | ||
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