2qe5: Difference between revisions
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Revision as of 14:51, 25 July 2012
Structure of HCV NS5B Bound to an Anthranilic Acid InhibitorStructure of HCV NS5B Bound to an Anthranilic Acid Inhibitor
Template:ABSTRACT PUBMED 17402724
About this StructureAbout this Structure
2qe5 is a 4 chain structure of RNA polymerase with sequence from Hepatitis c virus subtype 1b. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Nittoli T, Curran K, Insaf S, DiGrandi M, Orlowski M, Chopra R, Agarwal A, Howe AY, Prashad A, Floyd MB, Johnson B, Sutherland A, Wheless K, Feld B, O'Connell J, Mansour TS, Bloom J. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase. J Med Chem. 2007 May 3;50(9):2108-16. Epub 2007 Apr 3. PMID:17402724 doi:10.1021/jm061428x