1ad8: Difference between revisions

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-[[Image:1ad8.gif|left|200px]]<br /><applet load="1ad8" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ad8.gif|left|200px]]
-caption="1ad8, resolution 2.0&Aring;" />
-'''COMPLEX OF THROMBIN WITH AND INHIBITOR CONTAINING A NOVEL P1 MOIETY'''<br />
+ {{Structure
+|PDB= 1ad8 |SIZE=350|CAPTION= <scene name='initialview01'>1ad8</scene>, resolution 2.0&Aring;
+|SITE= <scene name='pdbsite=CAT:SER+Proteinase+Catalytic+Triad'>CAT</scene>
+|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=MDL:[DEHYDROXY-N-METHYL-TYROSYL-PROLINYL]-[4,4,5,5,5-PENTAFLUORO-3-OXY-1-[3-INDOLYL]-PENT-2-YL]AMINE'>MDL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
+|GENE=
+}}
+'''COMPLEX OF THROMBIN WITH AND INHIBITOR CONTAINING A NOVEL P1 MOIETY'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-AD8 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=MDL:'>MDL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Site: <scene name='pdbsite=CAT:SER+Proteinase+Catalytic+Triad'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AD8 OCA].
+AD8 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AD8 OCA].
 ==Reference==
-Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety., Malikayil JA, Burkhart JP, Schreuder HA, Broersma RJ Jr, Tardif C, Kutcher LW 3rd, Mehdi S, Schatzman GL, Neises B, Peet NP, Biochemistry. 1997 Feb 4;36(5):1034-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9033393 9033393]
+Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety., Malikayil JA, Burkhart JP, Schreuder HA, Broersma RJ Jr, Tardif C, Kutcher LW 3rd, Mehdi S, Schatzman GL, Neises B, Peet NP, Biochemistry. 1997 Feb 4;36(5):1034-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9033393 9033393]
 [[Category: Hirudo medicinalis]]
 [[Category: Homo sapiens]]
@@ Line 29: / Line 38: @@
 [[Category: serine protease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:43:18 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:55:56 2008''