1a72: Difference between revisions

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-[[Image:1a72.gif|left|200px]]<br /><applet load="1a72" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1a72.gif|left|200px]]
-caption="1a72, resolution 2.6&Aring;" />
-'''AN ACTIVE-SITE DOUBLE MUTANT (PHE93->TRP, VAL203->ALA) OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH THE ISOSTERIC NAD ANALOG CPAD'''<br />
+ {{Structure
+|PDB= 1a72 |SIZE=350|CAPTION= <scene name='initialview01'>1a72</scene>, resolution 2.6&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=PAD:5-BETA-D-RIBOFURANOSYLPICOLINAMIDE ADENINE-DINUCLEOTIDE'>PAD</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
+|GENE= F93W V203ALADH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9796 Equus caballus])
+}}
+'''AN ACTIVE-SITE DOUBLE MUTANT (PHE93->TRP, VAL203->ALA) OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH THE ISOSTERIC NAD ANALOG CPAD'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-A72 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=PAD:'>PAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A72 OCA].
+A72 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A72 OCA].
 ==Reference==
-Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes., Colby TD, Bahnson BJ, Chin JK, Klinman JP, Goldstein BM, Biochemistry. 1998 Jun 30;37(26):9295-304. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9649310 9649310]
+Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes., Colby TD, Bahnson BJ, Chin JK, Klinman JP, Goldstein BM, Biochemistry. 1998 Jun 30;37(26):9295-304. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9649310 9649310]
 [[Category: Alcohol dehydrogenase]]
 [[Category: Equus caballus]]
@@ Line 22: / Line 31: @@
 [[Category: ZN]]
 [[Category: active site mutant]]
-[[Category: isosteric nad inhibitors]]
+[[Category: isosteric nad inhibitor]]
 [[Category: liver alcohol dehydrogenase]]
 [[Category: oxidoreductase (nad(a)-choh(d))]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:41:41 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 09:53:49 2008''