Sandbox 122: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Student, Allison Granberry, Marisa L. VanBrakle

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 ==='''How does Kapβ2 identify its cargo?'''===
-<StructureSection load='2H4M' size=400 side=right scene='Sandbox_122/Kapb2_nls_blue_magenta/1'/Com_view/1'>
+<StructureSection load='2H4M' size=400 side=right scene='2H4M'/Com_view/1'>
 '''Structure of Kapβ2'''
-<scene name='Sandbox_122/Kapb2_nls_blue_magenta/1'> Kapβ2 </scene> is a superhelix comprised of 20 HEAT repeats (the name HEAT derives from Huntington, Elongation factor 3 A subunit of protein phosphatase 2A and Tor1 kinase), each of which consists of two anti-parallel helices. The electrostatic potential of the internal surface of Kapβ2 superhelix at the C-terminal arch is negative.
+<scene name='Sandbox_122/Kapb2_nls_blue_magenta/1'> Kap-β2 </scene> is a superhelix comprised of 20 HEAT repeats (the name HEAT derives from Huntington, Elongation factor 3 A subunit of protein phosphatase 2A and Tor1 kinase), each of which consists of two anti-parallel helices. The electrostatic potential of the internal surface of Kapβ2 superhelix at the C-terminal arch is negative.
-HEAT repeats 9-13 and 14-18 form the binding site of Kapβ2 cargos while repeats 1-8 constitute the Ran GTPase binding site.3 Ran GTPase, a small 216-residue protein, is found more frequently in the nucleus and enables cargos to be released from KapB2.
+HEAT repeats 9-13 and 14-18 form the binding site of Kapβ2 cargos while repeats 1-8 constitute the Ran GTPase binding site.3 Ran GTPase, a small 216-residue protein, is found more frequently in the nucleus and enables cargos to be released from Kapβ2.