13gs: Difference between revisions

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[[Image:13gs.gif|left|200px]]<br /><applet load="13gs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:13gs.gif|left|200px]]
caption="13gs, resolution 1.90&Aring;" />
 
'''GLUTATHIONE S-TRANSFERASE COMPLEXED WITH SULFASALAZINE'''<br />
{{Structure
|PDB= 13gs |SIZE=350|CAPTION= <scene name='initialview01'>13gs</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAS:2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC+ACID'>SAS</scene> and <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID'>MES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]
|GENE= GSTP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''GLUTATHIONE S-TRANSFERASE COMPLEXED WITH SULFASALAZINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
13GS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SAS:'>SAS</scene> and <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13GS OCA].  
13GS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13GS OCA].  


==Reference==
==Reference==
The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site)., Oakley AJ, Lo Bello M, Nuccetelli M, Mazzetti AP, Parker MW, J Mol Biol. 1999 Aug 27;291(4):913-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10452896 10452896]
The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site)., Oakley AJ, Lo Bello M, Nuccetelli M, Mazzetti AP, Parker MW, J Mol Biol. 1999 Aug 27;291(4):913-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10452896 10452896]
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: complex (transferase/sulfasalazine)]]
[[Category: complex (transferase/sulfasalazine)]]


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