Highest impact structures: Difference between revisions

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more initial creation
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m clarification
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More about some of the earliest structures and their PDB files is [http://www.umass.edu/microbio/rasmol/1st_xtls.htm here].  
More about some of the earliest structures and their PDB files is [http://www.umass.edu/microbio/rasmol/1st_xtls.htm here].  


* '''1953 - DNA double helix''' (B form): Although Watson and Crick's model was theoretical, it was correct, and for the first time explained the ability of genes to be faithfully copied during cell division. It was not confirmed by atomic resolution X-ray crystallography until 1973, using RNA dinucleotide crystals. A full turn of B form DNA was not solved until 1980 (cf. [[1bna]]), 27 years after Watson and Crick's model. More: click on DNA at the [http://atlas.molviz.org Atlas of Macromolecules]
* '''1953 - DNA double helix''' (B form): Although Watson and Crick's model was theoretical, it was essentially correct, and for the first time explained the ability of genes to be faithfully copied during cell division. It was not confirmed by atomic resolution X-ray crystallography until 1973, using RNA dinucleotide crystals. A full turn of B form DNA was not solved until 1980 (cf. [[1bna]]), 27 years after Watson and Crick's model. More: click on DNA at the [http://atlas.molviz.org Atlas of Macromolecules]


* '''1958 - Myoglobin''': As the first protein structure that was determined, it is hard to exaggerate its impact. Before this structure, there was very little understanding of 3D protein structure.
* '''1958 - Myoglobin''': As the first protein structure that was determined, it is hard to exaggerate its impact. Before this structure, there was very little understanding of 3D protein structure.

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Eric Martz, Joel Janin, Karsten Theis, Eran Hodis, Wayne Decatur, Adithya Sagar, Israel Hanukoglu, Joel L. Sussman