P53-DNA Recognition: Difference between revisions
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=A Base Pairing Variant Enhances p53 Binding to a Response Element= | =A Base Pairing Variant Enhances p53 Binding to a Response Element= | ||
[[Image:p53-intro.jpg|thumb|left|300px|Figure 1: Crystal structure of a p53 DBD tetramer-DNA complex; PDB ID# 3KZ8 ( | [[Image:p53-intro.jpg|thumb|left|300px|Figure 1: Crystal structure of a p53 DBD tetramer-DNA complex; PDB ID# 3KZ8 <ref name='kitayner'>Kitayner M, Rozenberg H, Rohs R, Suad O, Rabinovich D, Honig B, Shakked Z. Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs. Nat Struct Mol Biol. 2010;17(4):423-9<ref/>.]] | ||
[[Image:p53-domains.jpg|thumb|right|300px|domains]] | [[Image:p53-domains.jpg|thumb|right|300px|domains]] | ||