1bl8: Difference between revisions

Revision as of 09:29, 27 July 2012

Ligands:

Structural annotation:
Resources:	CATH : 1Bl8A00, 1Bl8B00, 1Bl8C00, 1Bl8D00 InterPro : Ipr003091, Ipr013099 Pfam : PF07885 SCOP : d1bl8a_, d1bl8b_, d1bl8c_, d1bl8d_ UniProt : P0A334

Functional annotation:
Cellular component:	integral to membrane membrane voltage-gated potassium channel complex
Biological process:	transport ion transport potassium ion transport
Molecular function:	ion channel activity voltage-gated potassium channel activity voltage-gated ion channel activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1bl8 is a 4 chain structure of Cation-pi interactions, Glutamate receptor (GluA2) and Potassium Channel with sequence from Streptomyces lividans. The February 2003 RCSB PDB Molecule of the Month feature on Potassium Channels by Shuchismita Dutta and David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_2. Full crystallographic information is available from OCA.

↑ Doyle DA, Morais Cabral J, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, Chait BT, MacKinnon R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science. 1998 Apr 3;280(5360):69-77. PMID:9525859
↑ Madden DR. The structure and function of glutamate receptor ion channels. Nat Rev Neurosci. 2002 Feb;3(2):91-101. PMID:11836517 doi:10.1038/nrn725
↑ Choe S. Potassium channel structures. Nat Rev Neurosci. 2002 Feb;3(2):115-21. PMID:11836519 doi:10.1038/nrn727
↑ Elliott DJ, Neale EJ, Aziz Q, Dunham JP, Munsey TS, Hunter M, Sivaprasadarao A. Molecular mechanism of voltage sensor movements in a potassium channel. EMBO J. 2004 Dec 8;23(24):4717-26. Epub 2004 Nov 25. PMID:15565171 doi:10.1038/sj.emboj.7600484

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