3c7q: Difference between revisions
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Revision as of 18:24, 2 June 2012
Structure of VEGFR2 kinase domain in complex with BIBF1120Structure of VEGFR2 kinase domain in complex with BIBF1120
Template:ABSTRACT PUBMED 18559524
About this StructureAbout this Structure
3c7q is a 1 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, Garin-Chesa P, Bader G, Zoephel A, Quant J, Heckel A, Rettig WJ. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy. Cancer Res. 2008 Jun 15;68(12):4774-82. PMID:18559524 doi:68/12/4774
- ↑ Roth GJ, Heckel A, Colbatzky F, Handschuh S, Kley J, Lehmann-Lintz T, Lotz R, Tontsch-Grunt U, Walter R, Hilberg F. Design, synthesis, and evaluation of indolinones as triple angiokinase inhibitors and the discovery of a highly specific 6-methoxycarbonyl-substituted indolinone (BIBF 1120). J Med Chem. 2009 Jul 23;52(14):4466-80. PMID:19522465 doi:10.1021/jm900431g
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Bader, G.
- Garin-Chesa, P.
- Heckel, A.
- Hilberg, F.
- Kautschitsch, S.
- Krssak, M.
- Quant, J.
- Rettig, W J.
- Roth, G J.
- Sommergruber, W.
- Tontsch-Grunt, U.
- Zoephel, A.
- Alpha beta
- Angiogenesis
- Atp-binding
- Developmental protein
- Differentiation
- Glycoprotein
- Host-virus interaction
- Immunoglobulin domain
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Receptor
- Transferase
- Transmembrane
- Tyrosine-protein kinase