2h2q: Difference between revisions

Revision as of 23:20, 25 July 2012

2h2q is a 2 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

↑ Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins. 2008 Dec;73(4):889-901. PMID:18536013 doi:10.1002/prot.22115

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 [[Image:2h2q.png|left|200px]]
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 ===Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase===
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