User:Jing Liu/Sandbox 1: Difference between revisions
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<Structure load='1L8Q' size='300' frame='true' align='right' caption='1L8Q' scene='User:Jing_Liu/Sandbox_1/1/4' /> | <Structure load='1L8Q' size='300' frame='true' align='right' caption='1L8Q' scene='User:Jing_Liu/Sandbox_1/1/4' /> | ||
This is a <scene name='User:Jing_Liu/Sandbox_1/1/4'>DnaA monomer strucure(Residues 76-399)</scene>, which contains <scene name='User:Jing_Liu/Sandbox_1/1/5'> | This is a <scene name='User:Jing_Liu/Sandbox_1/1/4'>DnaA monomer strucure(Residues 76-399)</scene>, which contains an <scene name='User:Jing_Liu/Sandbox_1/1/5'>ADP</scene> in it. | ||
=== DnaA function in Prokaryotes=== | === DnaA function in Prokaryotes=== | ||
DnaA is | DnaA is an AAA+ protein in prokaryotes for DNA replication initiation. To ensure correct timing of DNA replication, intracellular DnaA is under multi-level control, including changing expression/degradation level, regulator control and functional activation/inactivation by nucleotide-depedent conformational change. DnaA is a conserved protein in prokaryotes. In ''E. coli'', There are four regions in this protein: | ||
I: residues 1-85. DnaB loading domain; | |||
II: residues 86-133. linker region; | |||
III: residues 134-372. ATPase domain; | |||
IV: residues 373-467. DNA binding domain; | |||
=== Process of DNA Replication Initiation === | === Process of DNA Replication Initiation === | ||
Revision as of 15:37, 13 May 2012
One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground.
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This is a , which contains an in it.
DnaA function in ProkaryotesDnaA function in Prokaryotes
DnaA is an AAA+ protein in prokaryotes for DNA replication initiation. To ensure correct timing of DNA replication, intracellular DnaA is under multi-level control, including changing expression/degradation level, regulator control and functional activation/inactivation by nucleotide-depedent conformational change. DnaA is a conserved protein in prokaryotes. In E. coli, There are four regions in this protein:
I: residues 1-85. DnaB loading domain; II: residues 86-133. linker region; III: residues 134-372. ATPase domain; IV: residues 373-467. DNA binding domain;