Sandbox Reserved 470: Difference between revisions
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:The <scene name='Sandbox_Reserved_470/Gapdh-like_c-terminal_domain/3'>GAPDH-like, C-terminal domain</scene>GAPDH-like, C-terminal domain (Catalytic domain) is an Alpha Beta 2-Layer(α-β) Sandwich, including amino acids 139 - 300 on chains O and Q . Its CATH reports a holo-D-Glyceraldehyde-3-Phosphate Dehydrogenase, (domain 2) and a classification as an oxidoreductase (aldehyde(D)-NAD(A)). | :The <scene name='Sandbox_Reserved_470/Gapdh-like_c-terminal_domain/3'>GAPDH-like, C-terminal domain</scene>GAPDH-like, C-terminal domain (Catalytic domain) is an Alpha Beta 2-Layer(α-β) Sandwich, including amino acids 139 - 300 on chains O and Q . Its CATH reports a holo-D-Glyceraldehyde-3-Phosphate Dehydrogenase, (domain 2) and a classification as an oxidoreductase (aldehyde(D)-NAD(A)). | ||
*Depending on the environment, including variations in temperature and acidity, GAPDH can have different structural qualities and physical properties. In some cases, it is observed as a twinned structure with an α/β barrel. | *Depending on the environment, including variations in temperature and acidity, GAPDH can have different structural qualities and physical properties. In some cases, it is observed as a twinned structure with an α/β barrel. '''<ref>'''Watson, H.C., and J.C. Campbell. "Twinning In Crystals Of Human Skeletal Muscle D-Glyceraldehyde-3-Phosphate Dehydrogenase." RCSB Protein Data Bank. N.p., 27 Oct. 1983. Web. 28 Apr. 2012. '''[<www.rcsb.org/pdb/explore/explore.do?structureId=3gpd>]'''. '''</ref>''' | ||
[[Image:GAPDH homotetramer 2.png|400 px]] | [[Image:GAPDH homotetramer 2.png|400 px]] | ||
==Importance== | ==Importance== | ||