Sandbox Reserved 470: Difference between revisions
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GAPDH has two domains, a GAPDH-like, C-terminal domain, and an NAD Binding Domain. | GAPDH has two domains, a GAPDH-like, C-terminal domain, and an NAD Binding Domain. | ||
*The NAD (Nucleotide) Binding Domain is an Alpha Beta 3-Layer(α-β-α) Sandwich, including amino acids 1-138 and 301-340 on chains O and Q . Its [http://en.wikipedia.org/wiki/CATH CATH] reports a Rossmann fold and a classification as an [http://en.wikipedia.org/wiki/Oxidoreductase oxidoreductase]. | *The <scene name='Sandbox_Reserved_470/Nad_binding_domain/1'>NAD (Nucleotide) Binding Domain</scene> is an Alpha Beta 3-Layer(α-β-α) Sandwich, including amino acids 1-138 and 301-340 on chains O and Q . Its [http://en.wikipedia.org/wiki/CATH CATH] reports a Rossmann fold and a classification as an [http://en.wikipedia.org/wiki/Oxidoreductase oxidoreductase]. | ||
*The GAPDH-like, C-terminal domain (Catalytic domain) is an Alpha Beta 2-Layer(α-β) Sandwich, including amino acids 139 - 300 on chains O and Q . Its CATH reports a holo-D-Glyceraldehyde-3-Phosphate Dehydrogenase, (domain 2) and a classification as an oxidoreductase (aldehyde(D)-NAD(A)). | *The GAPDH-like, C-terminal domain (Catalytic domain) is an Alpha Beta 2-Layer(α-β) Sandwich, including amino acids 139 - 300 on chains O and Q . Its CATH reports a holo-D-Glyceraldehyde-3-Phosphate Dehydrogenase, (domain 2) and a classification as an oxidoreductase (aldehyde(D)-NAD(A)). | ||