3qb1: Difference between revisions
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{{STRUCTURE_3qb1| PDB=3qb1 | SCENE= }} | {{STRUCTURE_3qb1| PDB=3qb1 | SCENE= }} | ||
===Interleukin-2 mutant D10=== | ===Interleukin-2 mutant D10=== | ||
{{ABSTRACT_PUBMED_22446627}} | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN]] Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IL2_HUMAN IL2_HUMAN]] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. | |||
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==About this Structure== | ==About this Structure== | ||
[[3qb1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QB1 OCA]. | [[3qb1]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QB1 OCA]. | ||
==See Also== | |||
*[[Interleukin|Interleukin]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022446627</ref><references group="xtra"/> | <ref group="xtra">PMID:022446627</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bates, D L.]] | [[Category: Bates, D L.]] |