1m7b: Difference between revisions

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OCA

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 ==Overview==
-The Rnd proteins constitute an exceptional subfamily within the Rho GTPase, family. They possess extended chains at both termini and four prominent, amino acid deviations causing GTPase deficiency. Herein, we report the, crystal structure of the Rnd3/RhoE G-domain (amino acids 19-200) at 2.0 A, resolution. This is the first GTP-structure of a Rho family member which, reveals a similar fold but striking differences from RhoA concerning (i), GTPase center, (ii) charge distribution at several surface areas, (iii), C3-transferase binding site and (iv) interacting interfaces towards RhoA, regulators and effectors.
+The Rnd proteins constitute an exceptional subfamily within the Rho GTPase family. They possess extended chains at both termini and four prominent amino acid deviations causing GTPase deficiency. Herein, we report the crystal structure of the Rnd3/RhoE G-domain (amino acids 19-200) at 2.0 A resolution. This is the first GTP-structure of a Rho family member which reveals a similar fold but striking differences from RhoA concerning (i) GTPase center, (ii) charge distribution at several surface areas, (iii) C3-transferase binding site and (iv) interacting interfaces towards RhoA regulators and effectors.
 ==About this Structure==
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 [[Category: Homo sapiens]]
 [[Category: Single protein]]
-[[Category: Ahmadian, M.R.]]
+[[Category: Ahmadian, M R.]]
 [[Category: Blumenstein, L.]]
 [[Category: Fiegen, D.]]
 [[Category: Stege, P.]]
-[[Category: Vetter, I.R.]]
+[[Category: Vetter, I R.]]
 [[Category: GTP]]
 [[Category: MG]]
 [[Category: small gtpase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 16:22:23 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:52:17 2008''