Gp120: Difference between revisions
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{{STRUCTURE_3tgs| PDB=3tgs | SCENE= }} | {{STRUCTURE_3tgs| PDB=3tgs | SCENE= }} | ||
'''Glycoprotein Gp120''', named for its molecular weight, is found on the surface of HIV envelope. Gp120 is associated with Gp41. It is involved in the binding of HIV to CD4 receptors thus attaching the virus to the host cell. | |||
==3D structures of Gp120== | |||
===Gp120 from HIV=== | |||
[[3dnl]], [[3dnn]], [[3dno]], [[3tgq]], [[3tgr]], [[3tgt]], [[3tih]] - Gp120 core<br /> | |||
[[1meq]] – GP120 C5 domain – NMR<br /> | |||
[[1niz]], [[1nj0]] - GP120 V3 loop – NMR | |||
===Gp120 binary complex=== | |||
[[2ny7]] - Gp120 core (mutant) + antibody B12<br /> | |||
[[3idx]], [[3idy]] - Gp120 core (mutant) + antibody B13<br /> | |||
[[3hi1]] - Gp120 core + antibody F105<br /> | |||
[[3se8]], [[3se9]] - Gp120 + antibody VRC03<br /> | |||
[[3rjq]] - Gp120 core + antibody A12<br /> | |||
[[3u2s]] - Gp120 V1V2 region + antibody PG9<br /> | |||
[[3tgs]], [[4dko]], [[4dkp]], [[4dkq]], [[4dkr]] - Gp120 core + piperidine derivative | |||
===Gp120 ternary complex=== | |||
[[1gc1]], [[1g9m]], [[1g9n]], [[1rzj]], [[1rzk]], [[1yyl]], [[1yym]] – Gp120 core (mutant) + hCD4 N terminal (mutant) + antibody 17B<br /> | |||
[[2b4c]] - Gp120 core (mutant) + hCD4 N terminal + antibody X5<br /> | |||
[[2nxy]], [[2nxz]], [[2ny0]], [[2ny1]], [[2ny2]], [[2ny3]], [[2ny4]], [[2ny5]], [[2ny6]] - Gp120 core (mutant) + hCD4 N terminal + antibody 17B<br /> | |||
[[3jwd]], [[3jwo]] - Gp120 core + hCD4 N terminal + antibody 48D<br /> | |||
[[2i5y]], [[2i60]] - Gp120 core + hCD4 N terminal + antibody 17B<br /> | |||
===Gp120 from SIV=== | |||
[[2bf1]], [[3fus]] - Gp120 core | |||