3iu6: Difference between revisions

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-[[Image:3iu6.png|left|200px]]
-<!--
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 {{STRUCTURE_3iu6|  PDB=3iu6  |  SCENE=  }}
 ===Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1)===
+{{ABSTRACT_PUBMED_22464331}}
+==Disease==
+[[http://www.uniprot.org/uniprot/PB1_HUMAN PB1_HUMAN]] Defects in PBRM1 are a cause of renal cell carcinoma (RCC) [MIM:[http://omim.org/entry/144700 144700]]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma.<ref>PMID:21248752</ref>
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+==Function==
-The line below this paragraph, {{ABSTRACT_PUBMED_22464331}}, adds the Publication Abstract to the page
+[[http://www.uniprot.org/uniprot/PB1_HUMAN PB1_HUMAN]] Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.<ref>PMID:21248752</ref>
-(as it appears on PubMed at http://www.pubmed.gov), where 22464331 is the PubMed ID number.
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-{{ABSTRACT_PUBMED_22464331}}
 ==About this Structure==
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 ==Reference==
-<ref group="xtra">PMID:022464331</ref><references group="xtra"/>
+<ref group="xtra">PMID:022464331</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Arrowsmith, C H.]]