1afe: Difference between revisions

Revision as of 00:55, 26 July 2012

1afe is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

↑ De Simone G, Balliano G, Milla P, Gallina C, Giordano C, Tarricone C, Rizzi M, Bolognesi M, Ascenzi P. Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study. J Mol Biol. 1997 Jun 20;269(4):558-69. PMID:9217260 doi:10.1006/jmbi.1997.1037

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 [[Image:1afe.png|left|200px]]
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 ===HUMAN ALPHA-THROMBIN INHIBITION BY CBZ-PRO-AZALYS-ONP===
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