3v7p: Difference between revisions

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[[Image:3v7p.png|left|200px]]
==Crystal structure of amidohydrolase nis_0429 (target efi-500396) from Nitratiruptor sp. sb155-2==
 
<StructureSection load='3v7p' size='340' side='right' caption='[[3v7p]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
<!--
== Structural highlights ==
The line below this paragraph, containing "STRUCTURE_3v7p", creates the "Structure Box" on the page.
<table><tr><td colspan='2'>[[3v7p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitratiruptor_sp._sb155-2 Nitratiruptor sp. sb155-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V7P FirstGlance]. <br>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NIS_0429 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=387092 Nitratiruptor sp. SB155-2])</td></tr>
or leave the SCENE parameter empty for the default display.
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v7p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v7p RCSB], [http://www.ebi.ac.uk/pdbsum/3v7p PDBsum]</span></td></tr>
-->
</table>
{{STRUCTURE_3v7p|  PDB=3v7p  |  SCENE=  }}
== Function ==
 
[[http://www.uniprot.org/uniprot/A6Q234_NITSB A6Q234_NITSB]] Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2). To a lesser extent, can also deaminate 5'-methylthioadenosine.<ref>PMID:23972005</ref> 
===Crystal structure of amidohydrolase nis_0429 (target efi-500396) from Nitratiruptor sp. sb155-2===
== References ==
 
<references/>
 
__TOC__
==About this Structure==
</StructureSection>
[[3v7p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7P OCA].  
[[Category: Nitratiruptor sp. sb155-2]]
[[Category: Bacteria]]
[[Category: Almo, S C]]
[[Category: Almo, S C.]]
[[Category: Bhosle, R]]
[[Category: Bhosle, R.]]
[[Category: Chowdhury, S]]
[[Category: Chowdhury, S.]]
[[Category: Evans, B]]
[[Category: Evans, B.]]
[[Category: Gerlt, J A]]
[[Category: Gerlt, J A.]]
[[Category: Glenn, A Scott]]
[[Category: Glenn, A Scott.]]
[[Category: Hammonds, J]]
[[Category: Hammonds, J.]]
[[Category: Hillerich, B]]
[[Category: Hillerich, B.]]
[[Category: Imker, H J]]
[[Category: Imker, H J.]]
[[Category: Initiative, EfiEnzyme Function]]
[[Category: Initiative, EfiEnzyme Function.]]
[[Category: Patskovsky, Y]]
[[Category: Patskovsky, Y.]]
[[Category: Raushel, F M]]
[[Category: Raushel, F M.]]
[[Category: Seidel, R D]]
[[Category: Seidel, R D.]]
[[Category: Toro, R]]
[[Category: Toro, R.]]
[[Category: Washington, E]]
[[Category: Washington, E.]]
[[Category: Zencheck, W D]]
[[Category: Zencheck, W D.]]
[[Category: Amidohydrolase]]
[[Category: Amidohydrolase]]
[[Category: Efi]]
[[Category: Efi]]

Revision as of 12:16, 4 January 2015

Crystal structure of amidohydrolase nis_0429 (target efi-500396) from Nitratiruptor sp. sb155-2Crystal structure of amidohydrolase nis_0429 (target efi-500396) from Nitratiruptor sp. sb155-2

Structural highlights

3v7p is a 1 chain structure with sequence from Nitratiruptor sp. sb155-2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , , ,
Gene:NIS_0429 (Nitratiruptor sp. SB155-2)
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[A6Q234_NITSB] Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2). To a lesser extent, can also deaminate 5'-methylthioadenosine.[1]

References

  1. ↑ Goble AM, Toro R, Li X, Ornelas A, Fan H, Eswaramoorthy S, Patskovsky Y, Hillerich B, Seidel R, Sali A, Shoichet BK, Almo SC, Swaminathan S, Tanner ME, Raushel FM. Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. Biochemistry. 2013 Sep 17;52(37):6525-36. doi: 10.1021/bi400750a. Epub 2013 Sep, 4. PMID:23972005 doi:10.1021/bi400750a

3v7p, resolution 1.35Å

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