1akp: Difference between revisions
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{{STRUCTURE_1akp| PDB=1akp | SCENE= }} | {{STRUCTURE_1akp| PDB=1akp | SCENE= }} | ||
===SEQUENTIAL 1H,13C AND 15N NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF APOKEDARCIDIN=== | ===SEQUENTIAL 1H,13C AND 15N NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF APOKEDARCIDIN=== | ||
{{ABSTRACT_PUBMED_7918358}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KEDA_ACTSL KEDA_ACTSL]] Binds non-covalently to an enediyne chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore cleaves duplex DNA site-specifically in a single-stranded manner. The apoprotein cleaves proteins selectively, in particular highly basic histones, with H1 proteins being cleaved the more readily. | |||
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:007918358</ref><references group="xtra"/> | <ref group="xtra">PMID:007918358</ref><references group="xtra"/><references/> | ||
[[Category: Actinomycete atcc 53650]] | [[Category: Actinomycete atcc 53650]] | ||
[[Category: Bruccoleri, R E.]] | [[Category: Bruccoleri, R E.]] |