Sandbox 213: Difference between revisions
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<Structure load='3CLN' size='300' frame='true' align='left' caption='Calcium-bound calmodulin' scene='Insert optional scene name here' /> | <Structure load='3CLN' size='300' frame='true' align='left' caption='Calcium-bound calmodulin' scene='Insert optional scene name here' /> | ||
[[Calmodulin]] (CaM) for Calcium-Modulated protein is an important protein that intervenes in a wide range of activities. | [[Calmodulin]] (CaM) for Calcium-Modulated protein is an important protein that intervenes in a wide range of activities.<ref name="Najl V Valeyev1, Declan G Bates1, Pat Heslop-Harrison1,2, Ian Postlethwaite1 and Nikolay V Kotov. Elucidating the mechanisms of cooperative calcium-calmodulin interactions: a structural systems biology approach.BMC Systems Biology 2008, 2:48 doi:[[10.1186/1752-0509-2-48]]"/>. | ||
CaM is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. | CaM is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. | ||
Indeed, it is a small (16.7 kDa = 148 aa) and highly conserved protein that is necessary in all eukaryotic cells because it represents an essential calcium sensor with troponin C its isoform. | Indeed, it is a small (16.7 kDa = 148 aa) and highly conserved protein that is necessary in all eukaryotic cells because it represents an essential calcium sensor with troponin C its isoform. | ||