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== TSH and M22== | == TSH and M22== | ||
[[Image:TSHR 1.jpg | right]] | [[Image:TSHR 1.jpg | thumb | right]] | ||
TSH is a hormone also known as "thyrotropin". It is a member of the Glycoprotein Hormone Family or GHF(like hormones LH, FSH or hCG). TSH regulates the growth and the function of thyroid follicular cells by stimulating the secretion of thyroid hormones T3 and T4. These play an important role in human reproduction, metabolism and cellular development. Therefore, this class of receptors is central to medical, pharmaceutical, and biological research. | TSH is a hormone also known as "thyrotropin". It is a member of the Glycoprotein Hormone Family or GHF(like hormones LH, FSH or hCG). TSH regulates the growth and the function of thyroid follicular cells by stimulating the secretion of thyroid hormones T3 and T4. These play an important role in human reproduction, metabolism and cellular development. Therefore, this class of receptors is central to medical, pharmaceutical, and biological research. | ||
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== References == | == References == | ||
<ref> J. Sanders and co Crystal, Structure of the TSH Receptor in Complex with a Thyroid-Stimulating Autoantibody, THYROID Volume 17, Number 5, 2007 PMID:17542669 </ref> | |||
<ref> B R Smith, J Sanders, J Furmaniak, The TSH receptor – a new cristal structure, Hot Thyroidology Journal, article n°175</ref> | |||
<ref> V Vlaeminck-Guillem, G Vassart et S Costagliola, Un modèle d’activation du récepteur de la TSH / A THS receptor activation model, M/S : médecine sciences, vol. 18, n° 12, 2002, p. 1184-1186. </ref> | |||
== Proteopedia Page Contributors and Editors == | == Proteopedia Page Contributors and Editors == | ||
Nathalie FAGGIANELLI and Meriam ANNANI | Nathalie FAGGIANELLI and Meriam ANNANI | ||