3u2b: Difference between revisions
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{{STRUCTURE_3u2b| PDB=3u2b | SCENE= }} | {{STRUCTURE_3u2b| PDB=3u2b | SCENE= }} | ||
===Structure of the Sox4 HMG domain bound to DNA=== | ===Structure of the Sox4 HMG domain bound to DNA=== | ||
{{ABSTRACT_PUBMED_22181698}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SOX4_MOUSE SOX4_MOUSE]] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. | |||
-- | |||
==About this Structure== | ==About this Structure== | ||
[[3u2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3u2b]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2B OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022181698</ref><references group="xtra"/> | <ref group="xtra">PMID:022181698</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Lk3 transgenic mice]] | ||
[[Category: Jauch, R.]] | [[Category: Jauch, R.]] | ||
[[Category: Kolatkar, P R.]] | [[Category: Kolatkar, P R.]] | ||
Revision as of 17:17, 12 March 2014
Structure of the Sox4 HMG domain bound to DNAStructure of the Sox4 HMG domain bound to DNA
Template:ABSTRACT PUBMED 22181698
FunctionFunction
[SOX4_MOUSE] Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.
About this StructureAbout this Structure
3u2b is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Jauch R, Ng CK, Narasimhan K, Kolatkar PR. Crystal structure of the Sox4 HMG/DNA complex suggests a mechanism for the positional interdependence in DNA recognition. Biochem J. 2011 Dec 19. PMID:22181698 doi:10.1042/BJ20111768