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Molecular Playground/DHFR: Difference between revisions

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New page: <applet load='5dfr' size='400' color='white' frame='true' align='right' caption='Dihydrofolate Reductase (DHFR)''/> One of the CBI Molecules being studied in the [http://www.umass.ed...
 
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<applet load='5dfr' size='400' color='white' frame='true' align='right' caption='Dihydrofolate Reductase (DHFR)''/>
<applet load='5dfr' size='400' color='white' frame='true' align='right' caption='Dihydrofolate Reductase (DHFR) complex with Cl ions [[5dfr]]''/>


One of the [[CBI Molecules]] being studied in the  [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
One of the [[CBI Molecules]] being studied in the  [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
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===PDB structures===
===3D structures of DHFR===


[[5dfr]] - Apo E.coli DHFR
[[Dihydrofolate reductase]]  
 
[[7dfr]] - E.coli DHFR bound to Folate and NADP+
 
[[1u72]] - Human DHFR bound to NADP+ and Methotrexate
 
There are several other structures for DHFR from Human, E.coli and other species but are not shown here. You may refer to the pdb website for those. [http://www.pdb.org/pdb/results/results.do?qrid=FE767C1F&tabtoshow=Current]


===See Also===
===See Also===

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Karan Hingorani, Michal Harel
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