4a9n: Difference between revisions

Revision as of 09:28, 8 February 2012

4a9n is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Bamborough P, Diallo H, Goodacre JD, Gordon L, Lewis A, Seal JT, Wilson DM, Woodrow MD, Chung CW. Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides. J Med Chem. 2012 Jan 26;55(2):587-96. Epub 2012 Jan 11. PMID:22136469 doi:10.1021/jm201283q

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-'''Unreleased structure'''
+[[Image:4a9n.jpg|left|200px]]
-The entry 4a9n is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_4a9n", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a9n|  PDB=4a9n  |  SCENE=  }}
-Authors: Chung, C., Bamborough, P.
+===N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-cyclopropyl-5-(3,5- dimethyl-1,2-oxazol-4-yl)-2-methylbenzene-1-sulfonamide===
-Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH N-cyclopropyl-5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methylbenzene-1-sulfonamide
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22136469}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22136469 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22136469}}
+==About this Structure==
+[[4a9n]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9N OCA].
+==Reference==
+<ref group="xtra">PMID:022136469</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Bamborough, P.]]
+[[Category: Chung, C.]]
+[[Category: Signaling protein-inhibitor complex]]