Amyloid beta: Difference between revisions
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Catalase normally functions to convert hydrogen peroxide to hydrogen and water. If amyloid beta complexes with catalase at residues 31-35 catalase can no longer breakdown the toxic molecule. Is it thought that the inactivation of catalase is due to the insertion of the sulfur side chain of methionine into the catalytic site.<ref name="alz" /> | Catalase normally functions to convert hydrogen peroxide to hydrogen and water. If amyloid beta complexes with catalase at residues 31-35 catalase can no longer breakdown the toxic molecule. Is it thought that the inactivation of catalase is due to the insertion of the sulfur side chain of methionine into the catalytic site.<ref name="alz" /> | ||
==Prevention== | ==Prevention and Treatment== | ||
The most promising prevention of | Two major approaches have been taken to treating Alzheimer's; inhibiting the formation of APP and reducing the neurotoxic effects of amyloid beta itself. The most promising treatment the prevention of the enzymes responsible for creating APP, AF267B, which is a muscarinic receptor that activates aplha-secretase and reduces tau pathology.<ref name="alz" /> | ||
==References== | ==References== | ||
<references/> | <references/> | ||