Amyloid beta: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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 <StructureSection load=1iyt size='500' side='right' caption='amyloid-beta(1-42)', ([[1dm0]])' scene=''>
 ==Introduction==
-'''Alzheimer's disease''' is characterized by extracellular proteic plaques and intracellular neurofibrillary tangles.<ref name="structure">PMID: 12423364</ref> These plaques are collections of fibrils consisting mostly of beta-amyloid fibrils. These fibril may be aggregates of beta-sheets though it is also possible that the alpha helix forms pores in the membrane that trigger cell death.<ref name="structure" />
+'''Alzheimer's disease''' is characterized by extracellular proteic plaques and intracellular neurofibrillary tangles.<ref name="structure">PMID: 12423364</ref> These plaques are collections of fibrils consisting mostly of beta-amyloid <scene name='Amyloid_beta/Fibrils/1'>fibrils</scene>. These fibril are aggregates of beta-sheets though amyloid betam can also form alpha helices that create pores in the membrane that trigger cell death.<ref name="structure" />
 '''Amyloids''' are insoluble fibrous proteins