4a4x: Difference between revisions

Revision as of 12:12, 25 April 2012

4a4x is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Innocenti P, Cheung KM, Solanki S, Mas-Droux C, Rowan F, Yeoh S, Boxall K, Westlake M, Pickard L, Hardy T, Baxter JE, Aherne GW, Bayliss R, Fry AM, Hoelder S. Design of potent and selective hybrid inhibitors of the mitotic kinase nek2: structure-activity relationship, structural biology, and cellular activity. J Med Chem. 2012 Apr 12;55(7):3228-41. Epub 2012 Mar 23. PMID:22404346 doi:10.1021/jm201683b

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-'''Unreleased structure'''
+[[Image:4a4x.jpg|left|200px]]
-The entry 4a4x is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_4a4x", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a4x|  PDB=4a4x  |  SCENE=  }}
-Authors: Mas-Droux, C., Bayliss, R.
+===NEK2-EDE bound to CCT248662===
-Description: NEK2-EDE bound to CCT248662
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22404346}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22404346 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22404346}}
+==About this Structure==
+[[4a4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4X OCA].
+==Reference==
+<ref group="xtra">PMID:022404346</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Bayliss, R.]]
+[[Category: Mas-Droux, C.]]
+[[Category: Mitosis]]
+[[Category: Protein kinase]]
+[[Category: Transferase]]