Cluster of Differentiation CD38: Difference between revisions

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[[Image:3gc6a.jpg|left|200px|thumb|Crystal Structure of bovine Cluster of Differentiation 38 (CD38) [[3gc6]]]]
[[Image:3gc6a.jpg|left|200px|thumb|Crystal Structure of bovine Cluster of Differentiation 38 (CD38) [[3gc6]]]]
{{STRUCTURE_3gc6|  PDB=3gc6  | SIZE=300| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }}
{{STRUCTURE_3gc6|  PDB=3gc6  | SIZE=400| SCENE=Cluster_of_Differentiation_38/Cv/1 |right|CAPTION=Cluster of Differentiation 38 (CD38) complex with sulfate [[3gc6]] }}


[[Cluster of Differentiation 38]] (CD38), known also as [[ADP-ribosyl cyclase 1]] (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR).  It is found on the surface of immune cells.  It also functions in cell adhesion, signal transduction and Ca++ signaling. The images at the left and at the right correspond to one representative CD38, ''i.e.'' the crystal structure of bovine Cluster of Differentiation 38 ([[3gc6]]).
[[Cluster of Differentiation 38]] (CD38), known also as [[ADP-ribosyl cyclase 1]] (ADPRC1), catalyzes the synthesis and hydrolysis of cyclic ADP-ribose from NAD+ to ADP-ribose (ADPR).  It is found on the surface of immune cells.  It also functions in cell adhesion, signal transduction and Ca++ signaling. The images at the left and at the right correspond to one representative CD38, ''i.e.'' the crystal structure of bovine Cluster of Differentiation 38 ([[3gc6]]).

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Alexander Berchansky, Michal Harel, Jaime Prilusky