Theoretical models: Difference between revisions
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* [http://fold.it/portal/info/science Protein Folding Game called Foldit]: Are humans good at folding? Can crowdsourcing help the folding problem? Game to assess how well you folded a solved protein. <!--Anyone tried the Foldit game and know if it could be recommended on the High School page for students with great interest in exploring protein structure more?--> Structures given as folding puzzles aren't include solved structures and necessarily derived from theoretical; however, the goal of users is to produce a theoretical model that matches the known structure without referring to known structure. Check out [http://www.nature.com/nature/journal/v466/n7307/full/nature09304.html an article on it in Nature]<ref>PMID: 20686574</ref> and [http://www.biotechniques.com/news/Online-videogame-solves-protein-folding-problems/biotechniques-302088.html this coverage] of the project. | * [http://fold.it/portal/info/science Protein Folding Game called Foldit]: Are humans good at folding? Can crowdsourcing help the folding problem? Game to assess how well you folded a solved protein. <!--Anyone tried the Foldit game and know if it could be recommended on the High School page for students with great interest in exploring protein structure more?--> Structures given as folding puzzles aren't include solved structures and necessarily derived from theoretical; however, the goal of users is to produce a theoretical model that matches the known structure without referring to known structure. Check out [http://www.nature.com/nature/journal/v466/n7307/full/nature09304.html an article on it in Nature]<ref>PMID: 20686574</ref> and [http://www.biotechniques.com/news/Online-videogame-solves-protein-folding-problems/biotechniques-302088.html this coverage] of the project. | ||
* [http://www.ncbi.nlm.nih.gov/pubmed/20627589 Zhou and Robinson]<ref>PMID: 20627589 </ref> discuss integrating mass spectrometry and structural models to understand location of post-translational modifications. They include examples of superimposing homologous proteins in a complex and superposing on that the location of modifications to better understand complexes and the interactions of modified portions of proteins in such complexes. | * [http://www.ncbi.nlm.nih.gov/pubmed/20627589 Zhou and Robinson]<ref>PMID: 20627589 </ref> discuss integrating mass spectrometry and structural models to understand location of post-translational modifications. They include examples of superimposing homologous proteins in a complex and superposing on that the location of modifications to better understand complexes and the interactions of modified portions of proteins in such complexes. | ||
*[[RNaseA Nobel Prizes]] for discussion of protein folding. | * [[RNaseA Nobel Prizes]] for discussion of protein folding. | ||
* [[Complexes|Biological Complexes]] | |||
==References & Links== | ==References & Links== | ||
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