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== 3D Structures of thrombin==
== 3D Structures of thrombin==
===Thrombin===
[[3pmb]] - bThr HC + LC – bovine<br />
[[3qgn]] - hThr HC (mutant) + LC – human<br />
[[3r3g]] - hThr HC + LC <br />
[[2hnt]]– hThr-γ HC + LC<br />
[[3jz1]], [[3jz2]], [[2od3]] - hThr HC + LC (mutant) <br />
[[3gic]] - hThr HC + LC<br />
[[3ee0]], [[2a0q]], [[1sg8]], [[1sgi]], [[1jou]] - hThr HC (mutant) + LC<br />
[[3edx]], [[3hk3]], [[3hk6]] - mThr HC (mutant) + LC – mouse<br />
[[2ocv]] - mThr HC + LC
===Thrombin complexes===
[[3pma]] – bThr HC + LC residues 336-364 + sucrose octasulfate<br />
[[3hki]] - mThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />
[[3hkj]] - hThr HC (mutant) + LC + proteinase-activated receptor 1 peptide<br />
[[2pux]] - mThr HC + LC + proteinase-activated receptor 3 peptide<br />
[[2pv9]] - mThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
[[1dm4]] - mThr HC (mutant) + LC + fibrinogen peptide<br />
[[1ycp]], [[1bbr]] – bThr-ε HC + LC + fibrinogen peptide<br />
[[1ucy]] - bThr HC + LC + fibrinogen peptide<br />
[[1fph]] - hThr HC + LC + fibrinogen peptide<br />
[[3bv9]] - hThr HC (mutant) + LC + peptide inhibitor<br />
[[2a2x]], [[1eb1]], [[1h8i]], [[1h8d]], [[1dit]], [[1hbt]] - hThr HC + LC + peptide inhibitor<br />
[[1g37]], [[1eoj]], [[1eol]], [[1nrn]], [[1nro]], [[1nrp]], [[1nrq]], [[1nrr]], [[1nrs]] - hThr HC + peptide inhibitor<br />
[[1hlt]] - hThr HC + LC + thrombomodulin peptide<br />
[[2ank]] - hThr HC + LC + peptide + inhibitor<br />
[[1bhx]], [[1abj]], [[1ppb]] - hThr HC + LC + inhibitor<br />
[[1uvs]], [[1uvt]], [[1uvu]] - bThr HC + LC + inhibitor<br />
[[1etr]], [[1ets]], [[1ett]] – bThr-ε HC + LC + inhibitor<br />
[[3dd2]] - hThr HC + LC + RNA<br />
[[1hao]], [[1hap]], [[1hut]] - hThr HC + LC + DNA<br />
[[3bf6]] - hThr HC + LC + suramin<br />
[[1xmn]] - hThr HC + LC + heparin<br />
[[2h9t]] - hThr HC + LC + suramin + PPACK<BR />
[[1z8i]], [[1z8j]] - hThr HC + LC (mutant) + PPACK<BR />
[[1sfq]], [[1shh]], [[2thf]], [[1thp]], [[1b7x]] - hThr HC (mutant) + LC + PPACK<BR />
[[1ook]] - hThr HC + LC + PPACK<BR />
[[2hpp]], [[2hpq]] - hThr HC + LC + PThr residues 214-292 + PPACK<BR />
===Thrombin complexes containing hirudin===
[[3c27]], [[2zc9]], [[2zda]], [[2zdv]], [[3egk]], [[2r2m]], [[2v3h]], [[2v3o]], [[2pks]], [[3eq0]], [[3dt0]], [[3dux]], [[3da9]], [[3dhk]], [[2znk]], [[2zo3]], [[3d49]], [[2zhe]], [[2zhf]], [[2zhw]], [[2zg0]], [[2zfq]], [[2zfr]], [[2zhq]], [[2zi2]], [[2ziq]], [[2zff]], [[2zfp]], [[2zgb]], [[2zgx]], [[2zf0]], [[3biu]], [[3biv]], [[2uuj]], [[2uuk]], [[2jh0]], [[2jh5]], [[2jh6]], [[2gde]], [[2bxt]], [[2bxu]], [[2bvr]], [[2bvs]], [[2bvx]], [[2bdy]], [[2feq]], [[2c8w]], [[2c8x]], [[2c8y]], [[2c8z]], [[2c90]], [[2c93]], [[2cf8]], [[2cf9]], [[2anm]], [[2w7g]], [[2fes]], [[1ype]], [[1ypg]], [[1ypj]], [[1ypk]], [[1ypl]], [[1ypm]], [[1vzq]], [[1way]], [[1wbg]], [[1riw]], [[1mu6]], [[1mu8]], [[1mue]], [[1nzq]], [[1o0d]], [[1oyt]], [[1o2g]], [[1gj4]], [[1gj5]], [[1kts]], [[1ktt]], [[1ghv]], [[1ghw]], [[1ghx]], [[1ghy]], [[1c5n]], [[1c5o]], [[1c4y]], [[1d3d]], [[1d3p]], [[1d3q]], [[1d3t]], [[1c4u]], [[1c4v]], [[1c1u]], [[1c1v]], [[1c1w]], [[1qj1]], [[1qj6]], [[1qj7]], [[1qhr]], [[1qur]], [[1d4p]], [[1ba8]], [[1bb0]], [[1ca8]], [[1awf]], [[1awh]], [[1bcu]], [[1a61]], [[1a3b]], [[1a3e]], [[1a46]], [[1a5g]], [[1b5g]], [[1tbz]], [[1a4w]], [[1ay6]], [[1ae8]], [[1afe]], [[1ad8]], [[1ai8]], [[1aix]], [[1bmm]], [[1bmn]], [[1lhc]], [[1lhd]], [[1lhe]], [[1lhf]], [[1lhg]], [[1uma]], [[1aht]], [[1fpc ]] - hThr HC + LC + hirudin peptide + inhibitor<br />
[[1zgi]], [[1zgv]], [[1zrb]], [[1z71]], [[1xm1]], [[1sl3]], [[1ta2]], [[1ta6]], [[1nm6]], [[1nt1]], [[1doj]], [[1d9i]], [[1d6w]], [[1qbv]], [[1tmu]], [[1dwb]], [[1dwc]], [[1dwd]], [[1dwe]] - hThr HC + hirudin peptide + inhibitor<br />
[[1ny2]], [[8kme]], [[7kme]], [[1a2c]], [[1tom]], [[1hdt]], [[1tmt]], [[1tmb]] - hThr HC + LC + hirudin peptide + peptide inhibitor<br />
[[3hat]] - hThr HC + LC + hirudin peptide + fibrinogen peptide<br />
[[2uuf]], [[2pw8]], [[1no9]], [[1c5l]], [[1vr1]], [[4thn]], [[5gds]], [[1hxf]], [[1hxe]], [[1abi]], [[1hgt]], [[1ihs]], [[1iht]], [[1thr]], [[1ths]], [[2hgt]] - hThr HC + LC + hirudin peptide<br />
[[1vit]] - bThr HC + LC + hirudin peptide<br />
===Thrombin complex with protein===
[[2a45]] - hThr HC + LC + fibrinogen α, β, γ chains<br />
[[2a1d]], [[1nu7]] – bThr HC + LC + staphylocoagulase<br />
[[1tb6]] - hThr HC + LC (mutant) + antithrombin<br />
[[1jmo]] - hThr HC (mutant) + LC + heparin cofactor<br /> II
[[1e0f]] - hThr HC + LC + haemadin
[[1dx5]] - hThr HC + LC + thrombomodulin
[[3p6z]] - hThr HC + LC + coagulation factor V<br />
[[3pmh]] - hThr HC + LC + platelet glycoprotein IB α chain<br />
[[1avg]] - bThr HC + LC + triabin<br />
[[1bth]] - bThr HC (mutant) + LC (mutant) + BPTI<br />
[[1toc]] - bThr HC + LC + ornithodorin<br />
[[1tbq]], [[1tbr]] - bThr HC + LC + rhodniin<br />
[[1hrt]] - bThr HC + LC + hirudin<br />
[[3htc]], [[4htc]] - hThr HC + LC + hirudin
===Prothrombin===
[[3e6p]], [[2afq]] - hPThr HC + LC<br />
[[3s7h]], [[3s7k]]– hPThr HC + LC (mutant) <br />
[[3bei]], [[2pgb]], [[2gp9]], [[1tq0]], [[1rd3]] - hPThr HC (mutant) + LC<br />
[[1mh0]] - hPThr HC (mutant) <br />
[[1nl1]], [[1nl2]], [[2spt]], [[2pf1]], [[2pf2]] – bPThr residues 1-156
===Prothrombin complexes===
[[3qdz]] – hPThr HC (mutant) + LC + proteinase-activated receptor 4 peptide<br />
[[3lu9]], [[3bef]] - hPThr HC + LC (mutant) + proteinase-activated receptor 1 peptide<br />
[[3k65]] - hPThr HC residues 315-622 (mutant) + LC residues 199-314<br />
[[3f68]] - hPThr HC residues 364-622 + LC residues 328-363 + hirudin peptide<br />
[[1jwt]], [[3c1k]] - hPThr HC + inhibitor<br />
[[2pgq]], [[1tq7]] - hPThr HC (mutant) + LC + PPACK<BR />
[[2cn0]], [[1t4u]], [[1t4v]], [[1sb1]], [[1k21]], [[1k22]], [[1g30]], [[1g32]] - hPThr HC + LC + hirudin peptide + inhibitor<br />
[[1twx]] - hPThr HC (mutant) + LC + hirudin peptide<br />
[[2hwl]] - hPThr HC (mutant) + LC + fibrinogen γ’ peptide<br />
===Prothrombin complex with protein===
[[1id5]] - hPThr HC + LC + ecotin<br />
[[1p8v]] - hPThr HC + LC + platelet glycoprotein IB α chain<br />
[[3gis]] - hPThr HC residues 364-622 (mutant) + LC residues 315-363 + thrombomodulin<br />
[[3b9f]] - hPThr HC (mutant) + LC + protein C inhibitor<br />
[[2ody]] - hPThr HC + LC + boophilin
===Prethrombin-1===
[[3nxp]] - hThr residues 199-622
===Prethrombin-2===
[[1nu9]] – hThr HC + LC + staphylocoagulase<br />
[[1mkw]], [[1mkx]] – bThr + Thr HC + LC<br />
[[1hag]], [[1hah]] – hThr HC + LC + hirudin peptide<br />
[[1hai]] – hThr HC + LC + inhibitor<br />




[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Cody Couperus, Joel L. Sussman
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